Denaturation Fingerprinting: Two Related Mutation Detection Methods Especially Advantageous for High G+C Regions
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چکیده
منابع مشابه
Denaturation fingerprinting: two related mutation detection methods especially advantageous for high G + C regions.
Two versions of denaturation fingerprinting (dnF2R and dnF1R are described for detecting mutations. DnF2R is a sensitive screening method in which fingerprints are generated by performing denaturing gel electrophoresis on bidirectional "cycle-sequencing" reactions with each of two dideoxy terminators, e.g. ddATP and ddCTP. When the fingerprints generated by ddATP and ddCTP are combined, all seq...
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ژورنال
عنوان ژورنال: BioTechniques
سال: 1998
ISSN: 0736-6205,1940-9818
DOI: 10.2144/98241rr01